A Comparative Study on Comorbidities of Hospitalized Chronic Obstructive Pulmonary Disease (COPD) Patients Vs non-COPD Hospitalized Patients.

Auhtor: MA Helal, UK Das, M Shahjahan, A Barua, AMS Uddin, R Hasan

Abstract:

Background: Chronic obstructive pulmonary disease (COPD) is predominantly caused by long-term smoking, which results in pulmonary inflammation that is often associated with systemic inflammation. A number of comorbid conditions, such as cardiovascular disease, type 2 diabetes, muscle wasting, osteoporosis and tuberculosis may coexist with COPD; these and other co-morbidities not directly related to COPD are major causes of excess morbidity and mortality. The aim of this study is to compare the prevalence of co morbidities among the patients of COPD and non COPD patients admitted in a tertiary care hospital. Methods: Among total patients n=150, Cases were n1 =75 diagnosed COPD patients admitted in the hospital as per inclusion criteria and control were n2 =75 non COPD patients admitted in the hospital due to other common diseases. Co morbid diseases were evaluated among the case and control. Data were analyzed by frequency, mean, standard deviation, percentages, odds ratio with the help of computer based software SPSS-15. Odds ratio was considered as statistically significant when it is >1 with confidence interval = 95%. Results: Co-morbidities were more frequent among the patients of COPD than non COPD hospitalized patients. The results also was statistically significant (Odds ratio=2.6). Common co morbidities were diabetes mellitus, ischemic heart disease, pneumonia, hypertension, lung cancer, and tuberculosis. Conclusions: In order to provide the best possible care for people with COPD, the physician should be aware of all potential co- morbidities that may arise, and the critical role in effective management of these co-morbidities can play in improving patient outcomes.

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