Comparison of liver biopsy with fibroscan and other methods in predictivng fibrosis in chronic hepatitis B patients - a hospital based study

Auhtor: MN Islam, MF Karim, MA Mahtab, ABM Adnan, PK Poddar, MA Jalil

Abstract:

Introduction: Fibroscan is one of the recently introduced procedures in Bangladesh. It is used for assessing liver fibrosis non-invasively in liver diseases. The present study is done to assess its role as compared to other established methods in chronic hepatitis B patients. Methodology: Patients seeking treatment for chronic liver disease related to hepatitis B virus at outdoor or indoor of Department of Hepatology in Sir Salimullah Medical College Mitford Hospital were studied. These patients had compensated liver disease with no ascites, encephalopathy or jaundice. Here parameters of assessing liver fibrosis like liver biopsy, which is the gold standard, was compared with non-invasive tools like ultrasound, Fibroscan of liver, Aspartate Aminotransferase-to-Platelet ratio (APRI) index & Fibrosis-4 (FIB-4) scoring, Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) and Hepatitis B virus (HBV) DNA level.

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